About Dairy Wellness

Properly time vaccinations for reproductive success
Posted by Vic Cortese

Vaccinating against reproductive diseases helps keep cows pregnant, which can protect your reproductive program and bottom line. Timing is everything when it comes to successful reproductive programs, and that includes timing of vaccinations to help prevent reproductive diseases. Following the timing guidelines on product labels is critically important to helping guarantee safety and efficacy.

Understand MLV vaccines

Different types of vaccines, such as a modified-live viral (MLV) or killed vaccine, can stimulate the immune system in different ways. MLV vaccines contain live viruses that undergo limited replication within the body, while killed vaccines use dead microorganisms.

MLV vaccines closely mimic a natural infection, since the animal is actually seeing the modified pathogen in a more natural form. As a result, MLV vaccines can help create an effective, a balanced and (what should be) an entire immune response.

Studies involving infectious bovine rhinotracheitis (IBR) virus vaccines have demonstrated the safety and efficacy of MLV vaccines, such as the line of BOVI-SHIELD GOLD FP® vaccines for helping protect pregnant heifers, cows and their fetuses.* Cattle vaccinated with BOVI-SHIELD GOLD FP within the preceding 12 to 17 months and then vaccinated during each trimester of pregnancy had abortion rates similar to the control group, which was vaccinated with a placebo.1-3

MLV vaccines are safe to use, but there are risks involved when using them in pregnant cattle. Using these vaccines against their label directions and without supervision from a veterinarian are the biggest risks of all.

Take steps to help protect your herd

  • Regularly consult with your veterinarian to select vaccines and set up protocols.
  • Write vaccination protocols and include timing guidelines.
  • Keep accurate records that include vaccine administration dates.

Risk-free protection for your herd

With the Fetal Protection (FP) Guarantee, Zoetis ensures your herd will be free of IBR abortions if the cows and heifers were vaccinated according to label directions at least 30 days prebreeding with any of Zoetis’ family of FP vaccines.** In addition, Zoetis guarantees 100% of calves will be born free of bovine viral diarrhea (BVD) persistent infection (PI) provided that all cows and heifers have been vaccinated according to label direction at least 30 days prebreeding.


*Do not use in pregnant cattle (abortions can result) unless they are vaccinated, according to label directions, with any BOVI-SHIELD GOLD FP or PREGGUARD GOLD FP vaccine prebreeding initially and within 12 months thereafter. Do not use in calves nursing pregnant cows unless their dams were vaccinated within the past 12 months as described above. To help ensure safety in pregnant cattle, heifers must receive at least 2 doses of any BOVI-SHIELD GOLD FP or PREGGUARD GOLD FP vaccine with the second dose administered approximately 30 days prebreeding. 

**The Zoetis 100% BVD PI-Free Guarantee and the IBR Abortion Guarantee will be administered through Zoetis VMIPS (Veterinary Medical Information and Product Support) at 800-366-5288. Proof of purchase is required. Calves born to BVD PI-positive cows or heifers do not qualify for the guarantee. This guarantee does not apply to, and Zoetis shall not be liable for, any (x) damages caused as a result of the improper handling, misuse or abuse of the vaccines that are the subject of this guarantee, or the willful misconduct or negligence of any third party, or (y) any indirect, punitive, special, incidental or consequential damages. Zoetis reserves the right to modify or cancel the terms and conditions of this guarantee.

1 Data on file, Study Report No. 2434H-60-02-048, Zoetis Inc.

2 Data on file, Study Report No. 2434H-60-02-049, Zoetis Inc.

3 Data on file, Study Report No. 2434H-60-02-050, Zoetis Inc.

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